منابع مشابه
Beneficial Effects of Statins in Experimental Amnesia
The present study was undertaken to investigate the beneficial effects of widely-prescribed lipid lowering drugs, pitavastatin, atorvastatin and simvastatin 3-hydroxy-3-methylglutaryl-coenzyme-A (HMG-CoA) reductase inhibitors in cognitive dysfunctions of mice. Intra-cerebroventricular (ICV)-Streptozocin-(STZ)- and high-fat diet (HFD)-induced amnesia served as interoceptive memory models where a...
متن کاملbeneficial effects of statins in experimental amnesia
the present study was undertaken to investigate the beneficial effects of widely-prescribed lipid lowering drugs, pitavastatin, atorvastatin and simvastatin 3-hydroxy-3-methylglutaryl-coenzyme-a (hmg-coa) reductase inhibitors in cognitive dysfunctions of mice. intra-cerebroventricular (icv)-streptozocin-(stz)- and high-fat diet (hfd)-induced amnesia served as interoceptive memory models where a...
متن کاملAre statins beneficial for viral pneumonia?
R espiratory infections, primarily pneumonia and influenza, continue to be the leading infectious cause of death in the developed world [1, 2]. Despite the introduction of new classes of antibiotics there has been little progress in improving pneumonia-related outcomes since the widespread introduction of antibiotics in the 1940s [3]. In addition, there has been little progress on agents to pot...
متن کاملBeneficial cardiovascular pleiotropic effects of statins.
Pleiotropic effects of a drug are actions other than those for which the agent was specifically developed. These effects may be related or unrelated to the primary mechanism of action of the drug, and they are usually unanticipated. Pleiotropic effects may be undesirable (such as side effects or toxicity), neutral, or, as is especially the case with HMG-CoA reductase inhibitors (statins), benef...
متن کاملStatins: beneficial or adverse for glucose metabolism.
Large-scale clinical trials have established that statin use for lowering blood cholesterol is beneficial in reducing atherosclerotic cardiovascular diseases in different populations. However, the general reputation of statins seems to be clouded by a potential adverse effect of a class of statins on glucose metabolism. This paper reviewed clinical data of statins regarding the effects on diabe...
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ژورنال
عنوان ژورنال: Nature Reviews Cardiology
سال: 2014
ISSN: 1759-5002,1759-5010
DOI: 10.1038/nrcardio.2014.33